Description
Size
0,1 mg
Catalog no.:
PA2019
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Background
CETP(Cholesteryl Ester Transfer Protein Plasma), is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. CETP is also known as lipid transfer protein I(Day et al., 1994). Sparkes et al.(1987) used a CETP probe against DNA from a human/mouse somatic cell hybrid panel to assign the CETP gene to chromosome 16. Because the role of CETP in atherosclerosis remained unclear, Okamoto et al.(2000) attempted to develop a potent, specific CETP inhibitor. One inhibitor, JTT-705, forms a disulfide bond with CETP and increases high density lipoprotein(HDL) cholesterol, decreases non-HDL cholesterol, and inhibits the progression of atherosclerosis in rabbits.
Related articles
1. Day, J. R., Albers, J. J., Lofton-Day, C. E., Gilbert, T. L., Ching, A. F. T., Grant, F. J., O'Hara, P. J., Marcovina, S. M., Adolphson, J. L. Complete cDNA encoding human phospholipid transfer protein from human endothelial cells. J. Biol. Chem. 269: 9388-9391, 1994. 2. Okamoto, H., Yonemori, F., Wakitani, K., Minowa, T., Maeda, K., Shinkai, H. A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits. Nature 406: 203-207, 2000. 3. Sparkes, R. S., Drayna, D., Mohandas, T., Klisak, I., Heinzmann, C., Lawn, R., Lusis, A. J. Assignment of cholesterol ester transfer protein (CETP) gene to human 16q21. (Abstract) Cytogenet. Cell Genet. 46: 696 only, 1987.
Storage condtions
Keep the CETP Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
Synonyms
BPIFF antibody|CETP antibody|CETP_HUMAN antibody|Cholesteryl ester transfer antibody|Cholesteryl ester transfer protein antibody|Cholesteryl ester transfer protein plasma antibody|Cholesteryl ester transfer protein precursor antibody|HDLCQ10 antibody|Lipid transfer protein I antibody
Tips
The CETP Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human CETP(368-382aa PRPDQQHSVAYTFEE).
Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Gene Full Name
cholesteryl ester transfer protein, plasma
Protein Name
Cholesteryl ester transfer protein
Purification
Immunogen affinity purified.
Type of the antibody
IgG polyclonal antibody
Clone
Polyclonal antibody
Clonality
Polyclonal antibody
Product form
freeze-dried
French translation
anticorps
Uniprot ID
P11597
Raised in
rabbit
Reacts with species:
human
Gene Name
CETP
Target antigen
CETP
Analyses
WB