Description

Size

0,1 mg

Catalog no.:

PA2019

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Background

CETP(Cholesteryl Ester Transfer Protein Plasma), is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. CETP is also known as lipid transfer protein I(Day et al., 1994). Sparkes et al.(1987) used a CETP probe against DNA from a human/mouse somatic cell hybrid panel to assign the CETP gene to chromosome 16. Because the role of CETP in atherosclerosis remained unclear, Okamoto et al.(2000) attempted to develop a potent, specific CETP inhibitor. One inhibitor, JTT-705, forms a disulfide bond with CETP and increases high density lipoprotein(HDL) cholesterol, decreases non-HDL cholesterol, and inhibits the progression of atherosclerosis in rabbits.

Related articles

1. Day, J. R., Albers, J. J., Lofton-Day, C. E., Gilbert, T. L., Ching, A. F. T., Grant, F. J., O'Hara, P. J., Marcovina, S. M., Adolphson, J. L. Complete cDNA encoding human phospholipid transfer protein from human endothelial cells. J. Biol. Chem. 269: 9388-9391, 1994. 2. Okamoto, H., Yonemori, F., Wakitani, K., Minowa, T., Maeda, K., Shinkai, H. A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits. Nature 406: 203-207, 2000. 3. Sparkes, R. S., Drayna, D., Mohandas, T., Klisak, I., Heinzmann, C., Lawn, R., Lusis, A. J. Assignment of cholesterol ester transfer protein (CETP) gene to human 16q21. (Abstract) Cytogenet. Cell Genet. 46: 696 only, 1987.

Storage condtions

Keep the CETP Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.

Synonyms

BPIFF antibody|CETP antibody|CETP_HUMAN antibody|Cholesteryl ester transfer antibody|Cholesteryl ester transfer protein antibody|Cholesteryl ester transfer protein plasma antibody|Cholesteryl ester transfer protein precursor antibody|HDLCQ10 antibody|Lipid transfer protein I antibody

Tips

The CETP Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.

Properties

If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Solubilization

The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human CETP(368-382aa PRPDQQHSVAYTFEE).

Product configuration

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Gene Full Name

cholesteryl ester transfer protein, plasma

Protein Name

Cholesteryl ester transfer protein

Purification

Immunogen affinity purified.

Type of the antibody

IgG polyclonal antibody

Clone

Polyclonal antibody

Clonality

Polyclonal antibody

Product form

freeze-dried

French translation

anticorps

Uniprot ID

P11597

Raised in

rabbit

Reacts with species:

human

Gene Name

CETP

Target antigen

CETP

Analyses

WB